Employer / Commercial Insurance
Covered with requirementsWhat you need to qualify
- Age 18 and older
- BMI of 30 or higher
- Diagnosed obstructive sleep apnea (AHI of 15 or higher)
Qualification pathways
You can qualify through any one of these.
Initial Approval - Moderate to Severe OSA with Obesity
All of:
- Patient is >= 18 years of age
- Baseline BMI >= 30 kg/m2 (prior to any GLP-1 or GLP-1/GIP agonist)
- Sleep study showing diagnosis of moderate to severe OSA
- Sleep study showing apnea-hypopnea index (AHI) >= 15 events per hour
- Patient does NOT have central sleep apnea
- Patient does NOT have Cheyne Stokes respiration
- Medication will be used concomitantly with behavioral modification and a reduced-calorie diet
Continuation - Moderate to Severe OSA with Obesity
All of:
- Patient is >= 18 years of age
- Baseline BMI >= 30 kg/m2 (prior to any GLP-1 or GLP-1/GIP agonist)
- Patient has completed >= 1 year of therapy with Zepbound
- Patient has lost >= 10% of baseline body weight
- Prescriber attests patient has stability in OSA signs or symptoms
- Medication will be used concomitantly with behavioral modification and a reduced-calorie diet
Documentation to bring
- Baseline BMI documentation (>= 30 kg/m2, prior to any GLP-1 or GLP-1/GIP agonist)
- Sleep study results documenting moderate to severe OSA diagnosis
- Sleep study results documenting AHI >= 15 events per hour
- Confirmation patient does not have central sleep apnea or Cheyne Stokes respiration
- Documentation of >= 10% baseline body weight loss (continuation)
- Prescriber attestation of stability in OSA signs or symptoms (continuation)
Approval and renewal
- Initial approval: 12 months
- Renewal: every 12 months
- To renew, the plan looks for at least 10% weight loss from the starting weight and Continuation requires: >= 10% baseline body weight loss AND prescriber attestation of stability in OSA signs or symptoms (e.g., snoring, excessive daytime sleepiness, fatigue). Patient must have completed >= 1 year of initial therapy. PAP therapy status is NOT re-evaluated at continuation. OSA AHI is not re-measured at continuation. Make sure your starting weight and date are in the chart now — renewal is measured against it.
Not covered when
- Central sleep apnea is excluded
- Cheyne Stokes respiration is excluded
- Concomitant use with other GLP-1 agonists or GLP-1/GIP agonists is not covered
Policy note: PAP/CPAP trial is NOT required prior to approval; patients using PAP therapy or not using PAP therapy are both eligible. Sleep study must document AHI >= 15 events/hour but there is no specific timeframe requirement for how recent the sleep study must be (a prior requirement for within 1 year was removed in May 2025). Moderate OSA = AHI >= 15; Severe OSA = AHI >= 30. Continuation requires >= 10% body weight loss (higher than the 5% threshold for weight loss indication). No pediatric indication for OSA.
Policy effective April 15, 2026 · verified June 2, 2026 · source: cnf_684_coveragepositioncriteria_weight_loss_glp1_agonists_pa.pdf