Applies to Employer and ACA Marketplace plans.
Covered with requirementsQualification pathways
You can qualify through any one of these.
Initial Approval - Adult Weight Loss (BMI ≥ 30)
All of:
- Patient is ≥ 18 years of age
- Baseline BMI ≥ 30 kg/m2 (prior to any GLP-1 or GLP-1/GIP agonist)
- Patient has engaged in a trial of behavioral modification and dietary restriction for at least 3 months
- Medication will be used concomitantly with behavioral modification and a reduced-calorie diet
Initial Approval - Adult Weight Loss (BMI ≥ 27 with comorbidity)
All of:
- Patient is ≥ 18 years of age
- Baseline BMI ≥ 27 kg/m2 (prior to any GLP-1 or GLP-1/GIP agonist)
- Patient has engaged in a trial of behavioral modification and dietary restriction for at least 3 months
- Medication will be used concomitantly with behavioral modification and a reduced-calorie diet
Plus any one of:
- At baseline or currently: hypertension
- At baseline or currently: type 2 diabetes
- At baseline or currently: dyslipidemia
- At baseline or currently: obstructive sleep apnea
- At baseline or currently: cardiovascular disease
- At baseline or currently: knee osteoarthritis
- At baseline or currently: asthma
- At baseline or currently: COPD
- At baseline or currently: MASLD/NAFLD
- At baseline or currently: polycystic ovarian syndrome
- At baseline or currently: coronary artery disease
Continuation - Adult Weight Loss
All of:
- Patient is ≥ 18 years of age
- Baseline BMI ≥ 30 kg/m2 OR (BMI ≥ 27 kg/m2 with qualifying comorbidity) (prior to any GLP-1 or GLP-1/GIP agonist)
- Patient has lost ≥ 5% of baseline body weight
- Medication will be used concomitantly with behavioral modification and a reduced-calorie diet
- Patient has completed ≥ 8 months of initial therapy
Documentation to bring
- Baseline BMI documentation (≥ 30 kg/m2, or ≥ 27 kg/m2 with qualifying comorbidity, prior to any GLP-1 or GLP-1/GIP agonist)
- Documentation of at least 3-month trial of behavioral modification and dietary restriction (initial therapy)
- Documentation of qualifying weight-related comorbidity if baseline BMI 27-29.9 kg/m2
- Documentation of ≥ 5% baseline body weight loss (continuation)
Approval and renewal
- Initial approval: 8 months
- Renewal: every 12 months
- Renewal: Must have lost ≥ 5% of baseline body weight (baseline = prior to any GLP-1 or GLP-1/GIP agonist). Ongoing behavioral modification and reduced-calorie diet required. BMI threshold re-verified at continuation; 3-month lifestyle program not re-checked.
Not covered when
- Concomitant use with other GLP-1 agonists or GLP-1/GIP agonists is not covered
- Any use not meeting FDA-approved indications or criteria above is not medically necessary
Policy note: Zepbound weight loss indication is for adults only (age ≥ 18); no pediatric indication for weight loss. Initial approval is 8 months; continuation is 1 year. Baseline BMI is defined as prior to any GLP-1 or GLP-1/GIP agonist (not just prior to Zepbound).
Policy effective April 15, 2026 · verified June 2, 2026 · source: Cigna — GLP-1 coverage criteria (Policy 684) · View policy document (PDF)