Centene

Does Centene cover Mounjaro?

Quick answer · Type 2 Diabetes

Centene covers Mounjaro for type 2 diabetes with prior authorization on ACA Marketplace.

  • ACA Marketplace: Covered with requirements. Diagnosis documented with a code

Last verified June 2, 2026. Policy effective February 26, 2026. Source: CP.PMN.183.pdf. How we verify this data →

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Mounjaro for Type 2 Diabetes

What Centene requires, by plan type. Open this indication on its own page →

ACA Marketplace

Covered with requirements

What you need to qualify

  • Age 10 and older
  • Diagnosis documented with a code
  • Prior trial of 2 other GLP-1 medications (Victoza and Trulicity) for at least 90 days

Qualification pathways

You can qualify through any one of these.

T2DM with MASLD and overweight/obesity

All of:

  • Diagnosis of type 2 diabetes mellitus
  • Age >= 10 years
  • Diagnosis of MASLD
  • BMI 25-29.9 kg/m2 (overweight) or BMI >= 30 kg/m2 (obese)
  • Not prescribed concurrently with another GLP-1 receptor agonist or DPP-4 inhibitor
  • Dose does not exceed FDA-approved maximum (15 mg/week for adults, 10 mg/week for pediatrics)
  • Failure of both preferred GLP-1s: liraglutide (Victoza) for >= 3 consecutive months, then Trulicity for >= 3 consecutive months, unless clinically significant adverse effects, both contraindicated, or member has CKD and request is for Ozempic injection

T2DM with MASH

All of:

  • Diagnosis of type 2 diabetes mellitus
  • Age >= 10 years
  • Diagnosis of MASH
  • Failure of >= 3 consecutive month trial of pioglitazone unless contraindicated or clinically significant adverse effects
  • Not prescribed concurrently with another GLP-1 receptor agonist or DPP-4 inhibitor
  • Dose does not exceed FDA-approved maximum (15 mg/week for adults, 10 mg/week for pediatrics)
  • Failure of both preferred GLP-1s: liraglutide (Victoza) for >= 3 consecutive months, then Trulicity for >= 3 consecutive months, unless clinically significant adverse effects, both contraindicated, or member has CKD and request is for Ozempic injection

T2DM with ASCVD, high ASCVD risk, HFpEF, or CKD — agent with proven CV/renal benefit

All of:

  • Diagnosis of type 2 diabetes mellitus
  • Age >= 10 years
  • Mounjaro is an agent with proven cardiovascular benefit per 2026 ADA guidelines
  • Not prescribed concurrently with another GLP-1 receptor agonist or DPP-4 inhibitor
  • Dose does not exceed FDA-approved maximum (15 mg/week for adults, 10 mg/week for pediatrics)
  • Failure of both preferred GLP-1s: liraglutide (Victoza) for >= 3 consecutive months, then Trulicity for >= 3 consecutive months, unless clinically significant adverse effects, both contraindicated, or member has CKD and request is for Ozempic injection

Plus any one of:

  • Established atherosclerotic cardiovascular disease (ASCVD)
  • Indicators of high ASCVD risk (per Appendix D: age >= 55 with coronary/carotid/lower-extremity artery stenosis >50%, LVH, retinopathy, other end organ damage)
  • Heart failure with preserved ejection fraction
  • Chronic kidney disease
  • Failure of >= 3 consecutive months of SGLT2 inhibitor or SGLT2 inhibitor-containing product, unless clinically significant adverse effects or all contraindicated

T2DM without ASCVD, high ASCVD risk, HFpEF, CKD, MASLD, or MASH — non-GLP-1 step therapy

All of:

  • Diagnosis of type 2 diabetes mellitus
  • Age >= 10 years
  • No established ASCVD, indicators of high ASCVD risk, heart failure with preserved ejection fraction, CKD, MASLD, or MASH
  • Failure of >= 3 consecutive month trial of two agents from any of the following classes: biguanides, sulfonylureas, thiazolidinediones, DPP-4 inhibitors, SGLT2 inhibitors or SGLT2 inhibitor-containing products, unless clinically significant adverse effects or all contraindicated
  • Not prescribed concurrently with another GLP-1 receptor agonist or DPP-4 inhibitor
  • Dose does not exceed FDA-approved maximum (15 mg/week for adults, 10 mg/week for pediatrics)
  • Failure of both preferred GLP-1s: liraglutide (Victoza) for >= 3 consecutive months, then Trulicity for >= 3 consecutive months, unless clinically significant adverse effects, both contraindicated

Documentation to bring

  • Office chart notes, lab results, or other clinical information supporting all approval criteria
  • Documentation of type 2 diabetes mellitus diagnosis
  • Documentation of member age (>= 10 years)
  • Documentation of qualifying condition pathway (MASLD with overweight/obesity, MASH with pioglitazone trial/failure, ASCVD/high ASCVD risk/HFpEF/CKD with SGLT2i trial/failure, or two non-GLP-1 agent trial/failures)
  • Documentation of failure of liraglutide (Victoza) for >= 3 consecutive months (unless excepted)
  • Documentation of failure of Trulicity for >= 3 consecutive months after Victoza failure (unless excepted)
  • Confirmation that requested product is not prescribed concurrently with another GLP-1 receptor agonist or DPP-4 inhibitor

Approval and renewal

  • Initial approval: 12 months
  • Renewal: every 12 months
  • To renew, the plan looks for Member is responding positively to therapy. Continued therapy requires either (a) currently receiving medication via Centene benefit or previously met initial approval criteria, or (b) enrolled in a state with continuity of care regulations. No concurrent use with another GLP-1 or DPP-4 inhibitor.

Not covered when

  • Concurrent use with another GLP-1 receptor agonist
  • Concurrent use with a DPP-4 inhibitor
  • Dose exceeding FDA-approved maximum recommended dose
  • Type 1 diabetes

Policy note: Mounjaro is classified as a non-preferred GLP-1 receptor agonist requiring step therapy through liraglutide (Victoza) then Trulicity. Per 2026 ADA guidelines, Mounjaro was added as an agent with proven cardiovascular benefit. Age expansion to >= 10 years added per 2026 annual review. Mounjaro is a dual GLP-1/GIP receptor agonist but categorized under GLP-1 class policy. Pediatric maximum dose is 10 mg/week; adult maximum dose is 15 mg/week.

Policy effective February 26, 2026 · verified June 2, 2026 · source: CP.PMN.183.pdf

Why Mounjaro requests get denied by Centene

Based on what this policy asks for. Fix these before the first submission.

  1. Wrong brand for the diagnosis. Mounjaro and Zepbound are the same molecule with different approved uses; a request for Mounjaro under a diagnosis that matches Zepbound is routinely denied.
  2. Diagnosis code missing or wrong on the request.
  3. Required prior medication trials not documented.

Frequently asked questions

Does Centene cover Mounjaro?
Centene covers Mounjaro for type 2 diabetes with prior authorization on ACA Marketplace.
How long does a Mounjaro approval last with Centene?
Initial approvals last 12 months, and renewals are granted in 12-month periods.
What does Centene require to renew Mounjaro?
Member is responding positively to therapy. Continued therapy requires either (a) currently receiving medication via Centene benefit or previously met initial approval criteria, or (b) enrolled in a state with continuity of care regulations. No concurrent use with another GLP-1 or DPP-4 inhibitor.
How current is this information?
This page reflects Centene's written policy as of February 26, 2026, last verified against the source document on June 2, 2026.

Other medications under Centene

Mounjaro coverage under other plans

All insurance plans · All medications

This page summarizes Centene's written prior-authorization policy. It is not a guarantee of coverage; plans vary by employer and benefit design. Verify with your plan before relying on it.