Applies to Employer and ACA Marketplace plans.
Covered with requirementsQualification pathways
You can qualify through any one of these.
Adult weight management (BMI ≥ 30)
All of:
- Patient is an adult (18 years of age or over)
- BMI ≥ 30 kg/m^2
- Obesity is NOT restricted from coverage under the patient's benefit
- Patient is new to therapy, new to Prime, or attempting a repeat weight loss course of therapy
- Patient has been on a weight loss regimen of low-calorie diet, increased physical activity, and behavioral modifications for a minimum of 6 months
- Patient will NOT use the requested agent in combination with another weight loss agent (e.g., Contrave, phentermine, Qsymia, Xenical)
- Patient will NOT use the requested agent in combination with another GLP-1 receptor agonist
- Patient does NOT have any FDA labeled contraindications to the requested agent
- Patient is currently on a weight loss regimen of a low-calorie diet, increased physical activity, and behavioral modifications AND will continue it
- Age is within FDA labeling for the requested indication OR there is support for use at patient's age
Plus any one of:
- Patient has NOT tried a targeted weight loss agent (e.g., Saxenda, Wegovy, Zepbound) in the past 12 months
- Patient tried a targeted weight loss agent for a previous course of therapy in the past 12 months AND prescriber anticipates success with repeating therapy
Adult weight management (BMI ≥ 25 - Asian descent)
All of:
- Patient is an adult (18 years of age or over)
- Patient is of South Asian, Southeast Asian, or East Asian descent
- BMI ≥ 25 kg/m^2
- Obesity is NOT restricted from coverage under the patient's benefit
- Patient is new to therapy, new to Prime, or attempting a repeat weight loss course of therapy
- Patient has been on a weight loss regimen of low-calorie diet, increased physical activity, and behavioral modifications for a minimum of 6 months
- Patient will NOT use the requested agent in combination with another weight loss agent
- Patient will NOT use the requested agent in combination with another GLP-1 receptor agonist
- Patient does NOT have any FDA labeled contraindications to the requested agent
- Patient is currently on a weight loss regimen of a low-calorie diet, increased physical activity, and behavioral modifications AND will continue it
- Age is within FDA labeling for the requested indication OR there is support for use at patient's age
Plus any one of:
- Patient has NOT tried a targeted weight loss agent in the past 12 months
- Patient tried a targeted weight loss agent for a previous course of therapy in the past 12 months AND prescriber anticipates success with repeating therapy
Adult weight management (BMI ≥ 27 with comorbidity)
All of:
- Patient is an adult (18 years of age or over)
- BMI ≥ 27 kg/m^2
- At least one weight-related comorbidity/risk factor/complication (e.g., hypertension, type 2 diabetes mellitus, obstructive sleep apnea, cardiovascular disease, dyslipidemia)
- Obesity is NOT restricted from coverage under the patient's benefit
- Patient is new to therapy, new to Prime, or attempting a repeat weight loss course of therapy
- Patient has been on a weight loss regimen of low-calorie diet, increased physical activity, and behavioral modifications for a minimum of 6 months
- Patient will NOT use the requested agent in combination with another weight loss agent
- Patient will NOT use the requested agent in combination with another GLP-1 receptor agonist
- Patient does NOT have any FDA labeled contraindications to the requested agent
- Patient is currently on a weight loss regimen of a low-calorie diet, increased physical activity, and behavioral modifications AND will continue it
- Age is within FDA labeling for the requested indication OR there is support for use at patient's age
Plus any one of:
- Patient has NOT tried a targeted weight loss agent in the past 12 months
- Patient tried a targeted weight loss agent for a previous course of therapy in the past 12 months AND prescriber anticipates success with repeating therapy
Pediatric weight management (age 12-17)
All of:
- Patient is pediatric (12 to 17 years of age)
- Obesity is NOT restricted from coverage under the patient's benefit
- Patient is new to therapy, new to Prime, or attempting a repeat weight loss course of therapy
- Patient has been on a weight loss regimen of low-calorie diet, increased physical activity, and behavioral modifications for a minimum of 6 months
- Patient will NOT use the requested agent in combination with another weight loss agent
- Patient will NOT use the requested agent in combination with another GLP-1 receptor agonist
- Patient does NOT have any FDA labeled contraindications to the requested agent
- Patient is currently on a weight loss regimen of a low-calorie diet, increased physical activity, and behavioral modifications AND will continue it
- Age is within FDA labeling for the requested indication OR there is support for use at patient's age
Plus any one of:
- BMI ≥ 95th percentile for age and sex
- BMI ≥ 30 kg/m^2
- BMI ≥ 85th percentile for age and sex AND at least one weight-related comorbidity/risk factor/complication (e.g., hypertension, dyslipidemia, type 2 diabetes, obstructive sleep apnea)
Documentation to bring
- Documentation of BMI ≥ 30 kg/m^2 (or ≥ 27 with comorbidity, or ≥ 25 if Asian descent, or BMI percentile for pediatric patients)
- Documentation of 6-month weight loss regimen (low-calorie diet, increased physical activity, behavioral modifications)
- Documentation of weight-related comorbidity if using the 27 kg/m^2 threshold
- Documentation of ancestry if using the 25 kg/m^2 Asian threshold
- Documentation that obesity is not restricted from coverage under the patient's benefit
Quantity limits
- 2.5 MG/0.5 ML vial — 4 Vials per 180 days (84-day)
- 5 MG/0.5 ML vial, 7.5 MG/0.5 ML vial, 10 MG/0.5 ML vial, 12.5 MG/0.5 ML vial, 15 MG/0.5 ML vial — 4 Vials per 28 days
- 2.5 MG/0.5 ML autoinjector — 4 Pens per 180 days (84-day)
- 5 MG/0.5 ML autoinjector, 7.5 MG/0.5 ML autoinjector, 10 MG/0.5 ML autoinjector, 12.5 MG/0.5 ML autoinjector, 15 MG/0.5 ML autoinjector — 4 Pens per 28 days
- 2.5 MG/0.6 ML KwikPen — 1 Pen per 180 days (84-day)
- 5 MG/0.6 ML KwikPen, 7.5 MG/0.6 ML KwikPen, 10 MG/0.6 ML KwikPen, 12.5 MG/0.6 ML KwikPen, 15 MG/0.6 ML KwikPen — 1 Pen per 28 days
Approval and renewal
- Initial approval: 12 months
- Renewal: every 12 months
- Renewal: For renewal (after 52 weeks on maximum-tolerated dose), patient must have achieved and maintained ≥ 5% weight loss from baseline. Patients with < 52 weeks on maximum-tolerated dose may also qualify without demonstrating weight loss. Renewal also requires: obesity not restricted from benefit, continuing current weight loss course of therapy, pediatric patients (12-17) must have current BMI ≥ 85th percentile for age and sex, not combining with another weight loss agent, maintaining low-calorie diet/increased physical activity/behavioral modifications, not combining with another GLP-1 agonist, and no FDA labeled contraindications.
- Renewal: At least 52 weeks on therapy before the first renewal.
Not covered when
- Combination with another weight loss agent (e.g., Contrave, phentermine, Qsymia, Xenical) not allowed
- Combination with another GLP-1 receptor agonist (e.g., Saxenda, Wegovy, Zepbound, Bydureon, Byetta, Mounjaro, Ozempic, Rybelsus, Trulicity, Victoza) not allowed
- Any FDA labeled contraindications to the requested agent
- Obesity restricted from coverage under the patient's benefit
Policy note: Zepbound available as vials, autoinjectors, and KwikPens — all covered. For continuation after 52 weeks on maximum-tolerated dose, patient must demonstrate ≥ 5% weight loss from baseline. Patients with < 52 weeks on maximum-tolerated dose may qualify for renewal without demonstrating weight loss. Policy also allows approval if patient has another FDA labeled indication for the requested agent. This weight loss entry excludes the OSA pathway, which is captured separately.
Policy effective June 1, 2026 · verified June 4, 2026 · source: Wy Weight Management Paql Prog Sum · View policy document (PDF)