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North Dakota Medicaid · Heart Disease Risk Reduction

North Dakota Medicaid coverage for Ozempic (Heart Disease Risk Reduction)

Medicaid

Covered with requirements

What you need to qualify

  • Age 55 to 74
  • BMI of 27 or higher
  • Established cardiovascular disease (MI, stroke, and PAD)
  • On guideline-directed medical therapy (lipid-lowering therapy and antiplatelet therapy)
  • Lab results confirming eligibility
  • Not being used to treat type 1 diabetes

Qualification pathways

You can qualify through any one of these.

MACE risk reduction - non-diabetic patients (Ozempic as step-therapy prerequisite for Wegovy injection)

All of:

  • Member is between ages ≥55 and <75
  • Member does not have diabetes, as evidenced by A1C within normal range without diabetes medication
  • Member has initial BMI ≥27 kg/m2 and <35 kg/m2
  • Member is concurrently taking lipid-lowering and antiplatelet therapy
  • Dose escalation to 2mg of Ozempic (semaglutide) must be tolerated before Wegovy injection will be authorized (2.4mg is the only strength indicated for reduction of MACE)

Plus any one of:

  • Prior myocardial infarction (MI)
  • Prior stroke AND peripheral arterial disease (PAD), as evidenced by intermittent claudication with ankle-brachial index <0.85, peripheral arterial revascularization procedure, or amputation due to atherosclerotic disease

Documentation to bring

  • A1C lab result within normal range (confirming no diabetes) without diabetes medication
  • Documentation of baseline BMI ≥27 kg/m2 and <35 kg/m2
  • Documentation of qualifying CV event (prior MI; OR prior stroke AND PAD with ABI <0.85, revascularization, or amputation)
  • Documentation of concurrent lipid-lowering therapy use
  • Documentation of concurrent antiplatelet therapy use
  • Tobacco cessation counseling documentation (if current tobacco user, within past year)
  • Documentation of dose escalation to Ozempic 2mg tolerated (required before Wegovy injection authorized)

Approval and renewal

  • Initial approval: 12 months
  • Renewal: every 12 months
  • To renew, the plan looks for at least 5% weight loss from the starting weight, at least 5% reduction in BMI, and For Wegovy injection: must have tolerated dose escalation to 2mg of Ozempic before Wegovy authorized. Failure defined as: unable to achieve weight loss ≥5% from baseline, OR unable to achieve reduction of BMI ≥5% from baseline, OR experienced a cardiovascular event following a 5% weight loss or 5% reduction of BMI since starting medication. Make sure your starting weight and date are in the chart now — renewal is measured against it.

Not covered when

  • Patients WITH diabetes are not eligible for this MACE indication (diabetes exclusion); they should use the diabetes criteria
  • BMI ≥35 kg/m2 is excluded from this MACE indication
  • Ozempic 2mg is required as step therapy before Wegovy injection for MACE

Policy note: Under the 'Reduction of Major Adverse Cardiovascular Events (MACE)' section, Ozempic is listed as a NON-PREFERRED injectable agent (Wegovy injection and Ozempic are both listed; Wegovy injection is also non-preferred; Wegovy tablets are non-preferred). For diabetic patients qualifying for MACE reduction, the document directs to the diabetes category criteria. The MACE section specifically addresses non-diabetic patients. Ozempic 2mg must be tolerated as a prerequisite step before Wegovy injection for MACE is authorized. The BMI range is ≥27 and <35 kg/m2.

Policy effective April 1, 2026 · verified June 3, 2026 · source: PDL-2026.4.pdf

All Ozempic policies under North Dakota Medicaid · Check your card