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North Carolina Medicaid · Weight Loss

North Carolina Medicaid coverage for Zepbound (Weight Loss)

Medicaid

Covered with requirements

What you need to qualify

  • Age 18 and older
  • BMI of 30 or higher
  • BMI of 27 or higher with a weight-related condition (HTN, T2DM, OSA, CVD, and dyslipidemia)
  • 6 months of a documented diet and exercise program

Qualification pathways

You can qualify through any one of these.

Adult (18+) — BMI ≥ 30

All of:

  • Age 18 or older
  • BMI ≥ 30 kg/m²
  • FDA approved for indication, age, weight, and does not exceed dosing limits
  • Preferred drug trial completed (3–6 months titration) unless contraindicated or meets non-preferred PDL PA criteria
  • Baseline weight and BMI documented within past 45 days on PA form
  • Beneficiary is new to therapy or attempting a repeat weight loss course
  • Currently on and will continue lifestyle modification (structured nutrition and physical activity)
  • Will NOT use in combination with another GLP-1 receptor agonist
  • No FDA-labeled contraindications (including pregnancy, lactation, medullary thyroid cancer history, MEN2)

Adult (18+) — BMI ≥ 27 with comorbidity

All of:

  • Age 18 or older
  • BMI ≥ 27 kg/m²
  • At least one weight-related comorbidity/risk factor/complication (hypertension, type 2 diabetes, obstructive sleep apnea, cardiovascular disease, dyslipidemia)
  • FDA approved for indication, age, weight, and does not exceed dosing limits
  • Preferred drug trial completed (3–6 months titration) unless contraindicated or meets non-preferred PDL PA criteria
  • Baseline weight and BMI documented within past 45 days on PA form
  • Beneficiary is new to therapy or attempting a repeat weight loss course
  • Currently on and will continue lifestyle modification (structured nutrition and physical activity)
  • Will NOT use in combination with another GLP-1 receptor agonist
  • No FDA-labeled contraindications (including pregnancy, lactation, medullary thyroid cancer history, MEN2)

Documentation to bring

  • Baseline weight and BMI (measured within the past 45 days) documented on PA form
  • Documentation of preferred drug trial (3–6 months titration) or documented contraindication to preferred drug
  • Documentation that beneficiary is new to therapy or attempting a repeat weight loss course
  • For BMI ≥ 27 with comorbidity pathway: documentation of qualifying weight-related comorbidity

Quantity limits

  • all strengths — 2 mL per 28 days

Approval and renewal

  • Initial approval: 6 months
  • Renewal: every 12 months
  • To renew, the plan looks for at least 5% weight loss from the starting weight, at least 4% reduction in BMI, and Adults: 5% total pretreatment weight loss maintained. Adolescents (12 to <18): >4% reduction in baseline BMI maintained. Alternatively, documented weight loss deemed significant per prescriber even if thresholds not met (with rationale). Continued lifestyle modification required. No combination with another GLP-1. No FDA-labeled contraindications. At each renewal, provider must document review of medication list for possible dose reductions or discontinuation of comorbid medications no longer needed due to weight reduction effects. Note: Zepbound for weight loss is only approved for adults (18+). Make sure your starting weight and date are in the chart now — renewal is measured against it.

Not covered when

  • Lactation
  • History of medullary thyroid carcinoma
  • Multiple endocrine neoplasia syndrome type 2 (MEN2)
  • Concurrent use with another GLP-1 receptor agonist
  • Patients under 18 years of age (Zepbound is 18 and over only)
  • Pregnancy

Policy note: Zepbound for weight loss is restricted to adults 18 and over, unlike Wegovy which has a lower age limit of 12. The general weight management policy also allows adults ≥ 45 with BMI ≥ 27 and established CVD (MI, stroke, symptomatic peripheral disease) as a qualifying pathway. Renewal duration is 12 months per the general weight management renewal section.

Policy effective August 1, 2024 · verified June 4, 2026 · source: download

All Zepbound policies under North Carolina Medicaid · Check your card