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Missouri Medicaid · Type 2 Diabetes

Missouri Medicaid coverage for Ozempic (Type 2 Diabetes)

Medicaid

Covered (preferred drug)

What you need to qualify

  • Trial of metformin for at least 365 days, or a documented reason it can't be used

Qualification pathways

You can qualify through any one of these.

Preferred agent — metformin trial

All of:

  • Ozempic is a preferred agent
  • Adequate therapeutic trial of metformin in the past year

Preferred agent — prior GLP-1 history

All of:

  • Ozempic is a preferred agent
  • Prior history with a GLP-1 agonist in the past 3 months

Documentation to bring

  • Documentation of adequate therapeutic trial of metformin in the past year OR documentation of prior GLP-1 agonist use in the past 3 months

Quantity limits

  • 0.25 mg/dose, 0.5 mg/dose (1.5 mL pen) — 1.5 mL per 28 days
  • 0.25 mg/dose (2 mg/3 mL pen), 1 mg/dose (2 mg/1.5 mL pen), 1 mg/dose (4 mg/3 mL pen), 2 mg/dose (8 mg/3 mL pen) — 3 mL per 28 days

Approval and renewal

  • Initial approval: 12 months
  • Renewal: every 12 months

Not covered when

  • Concurrent therapy with another GLP-1 receptor agonist

Policy note: Ozempic is a preferred agent on the MO HealthNet PDL. For preferred agents, approval requires either an adequate therapeutic trial of metformin in the past year OR prior history with a GLP-1 agonist in the past 3 months. Denial code '0160' (Preferred Drug List) applies when criteria not met. GLP-1 receptor agonists indicated for anti-obesity/obesity are covered under a separate PDL edit.

Policy effective January 9, 2025 · verified June 3, 2026 · source: policy-310.html

All Ozempic policies under Missouri Medicaid · Check your card