Employer / Commercial Insurance
Covered with requirementsWhat you need to qualify
- Age 45 and older
- BMI of 27 or higher
- Established cardiovascular disease (CV death, non-fatal MI, and non-fatal stroke)
- Not being used to treat type 1 diabetes
Qualification pathways
You can qualify through any one of these.
CV risk reduction in adults with established CVD and overweight/obesity without diabetes
All of:
- Age >= 45 years
- BMI >= 27 kg/m2
- Established cardiovascular disease
- Without diabetes (SELECT trial enrolled patients without diabetes)
Documentation to bring
- Documentation of established cardiovascular disease
- Baseline BMI >= 27 kg/m2
- Confirmation that patient does not have diabetes (SELECT trial basis)
Not covered when
- Concomitant use with other semaglutide-containing products not recommended
- Concomitant use with any other GLP-1 receptor agonist not recommended
- SELECT trial excluded patients with diabetes; document notes CV indication is independent of diabetes status per FDA label but trial population was without diabetes
Policy note: The SELECT trial (NCT03574597) enrolled adults >= 45 years with BMI >= 27 kg/m2, established CVD, and without diabetes. The document references this trial as supporting CV risk reduction. The FDA indication covers adults with established CV disease and either obesity or overweight. The clinical rationale notes the CV benefit is 'independent of diabetes status' but the trial itself excluded patients with diabetes, hence excludes_diabetes set to true based on trial population.
Policy effective May 4, 2026 · verified June 2, 2026 · source: RI_Weight_Management_ProgSum.pdf