Employer / Commercial Insurance
Depends on your plan's benefitExpanded indications must NOT be restricted from coverage under the patient's pharmacy benefit.
What you need to qualify
- Age 18 and older
- Prescribed by or in consultation with a specialist
- Confirmed MASH diagnosis by liver_biopsy, FibroScan_VCTE, ELF_test, and MRE, fibrosis stage F2 to F3
Qualification pathways
You can qualify through any one of these.
MASH with F2-F3 Fibrosis — Initial Approval
All of:
- Expanded indications are NOT restricted from coverage under the patient's pharmacy benefit
- Diagnosis of noncirrhotic MASH (formerly NASH) with moderate to advanced liver fibrosis (stages F2 to F3)
- Requested agent is Wegovy injection
- Patient is an adult (18 years of age or over)
- Stage F2 or F3 fibrosis confirmed by one of: liver biopsy, VCTE (e.g., FibroScan), ELF score, or MRE (prior to therapy)
- Patient is being monitored and/or treated for any comorbid conditions (e.g., cardiovascular disease, diabetes, dyslipidemia, hypertension)
- Patient does NOT have decompensated cirrhosis
- Patient does NOT have moderate to severe hepatic impairment (Child-Pugh Class B or C)
- Patient does NOT have any other liver disease (e.g., Wilson's disease, HCC, hepatitis)
- Prescriber is a specialist (e.g., hepatologist, gastroenterologist) or has consulted with a specialist
- Patient will NOT use the requested agent in combination with another weight loss agent
- Patient is currently on and will continue weight management regimen
- Patient will NOT use the requested agent in combination with another GLP-1 receptor agonist
- Patient does NOT have any FDA labeled contraindications
- Patient has tried and failed at least three formulary alternatives OR prescriber indicates alternatives are contraindicated, likely less effective, or likely to cause adverse reaction
Plus any one of:
- Female patient with alcohol consumption less than 20 grams/day
- Male patient with alcohol consumption less than 30 grams/day
Documentation to bring
- Medical records documenting diagnosis of noncirrhotic MASH with fibrosis stages F2 or F3
- Documentation of fibrosis staging confirmed by liver biopsy, VCTE (FibroScan), ELF score, or MRE (obtained prior to therapy initiation)
- Documentation of alcohol consumption (< 20 g/day for females; < 30 g/day for males)
- Documentation of monitoring/treatment for comorbid conditions (CVD, diabetes, dyslipidemia, hypertension)
- Documentation ruling out decompensated cirrhosis, Child-Pugh Class B or C hepatic impairment, and other liver diseases (Wilson's disease, HCC, hepatitis)
- Documentation of specialist involvement (hepatologist or gastroenterologist) or consultation
- Documentation of formulary alternatives tried and failed (at least 3), or clinical reason alternatives are contraindicated/less effective/harmful
Approval and renewal
- Initial approval: 12 months
- Renewal: every 12 months
- To renew, the plan looks for At renewal: patient must have clinical benefit with the requested agent. Alcohol limits (< 20 g/day female, < 30 g/day male) are re-verified. Exclusions for decompensated cirrhosis, Child-Pugh B/C, and other liver disease are re-verified. Specialist requirement is re-verified. Fibrosis staging confirmation (liver biopsy/VCTE/ELF/MRE) is NOT re-required at renewal.
Not covered when
- Decompensated cirrhosis
- Moderate to severe hepatic impairment (Child-Pugh Class B or C)
- Any other liver disease (e.g., Wilson's disease, hepatocellular carcinoma, hepatitis)
- Co-administration with another weight loss agent
- Co-administration with another GLP-1 receptor agonist
- Any FDA labeled contraindications
- Alcohol consumption >= 20 g/day (female) or >= 30 g/day (male)
Policy note: The MASH indication is an expanded indication. Fibrosis must be stage F2 or F3 (noncirrhotic). Fibrosis confirmation methods accepted: liver biopsy, VCTE (FibroScan), ELF score, or MRE — no lookback period explicitly stated in the policy. The policy does not explicitly state a FIB-4 score as a standalone qualifying confirmation method (though it is discussed in the clinical rationale). The policy requires monitoring/treatment of comorbidities. Alcohol limits align with MASLD definition: < 20 g/day female, < 30 g/day male. Managed by Prime Therapeutics.
Policy effective April 1, 2026 · verified June 5, 2026 · source: Pa policy