You can qualify through any one of these.
Initial Approval: Wegovy for CV Risk Reduction
All of:
- Age >= 45 years
- BMI >= 27 kg/m2
- Established cardiovascular disease (prior MI, prior ischemic or hemorrhagic stroke, or symptomatic PAD as defined below)
- HbA1c < 6.5% within past 12 months
- Does NOT have type 1 or type 2 diabetes (gestational diabetes excluded from this restriction)
- Does NOT have NYHA Class IV heart failure
- Where clinically appropriate, is on guideline-directed standard of care for CV condition (e.g., lipid-lowering therapy, platelet aggregation inhibitors, ACE inhibitors or ARBs, beta blockers, calcium channel blockers, ARNI)
- Will be used as adjunct to a program supporting reduced calorie diet (>= 500 kcal/day reduction) and >= 150 min/week activity
- Prescribed by or in consultation with a Cardiologist
- Failure, contraindication, or intolerance to THREE generic equivalents (if available) for at least 3 months each
- No personal or family history of medullary thyroid carcinoma or MEN2
- No prior serious hypersensitivity reaction to semaglutide
- No concomitant use of GLP-1 receptor agonists or GIP/GLP-1 agonists
- No chronic pancreatitis or recent (within 180 days) acute pancreatitis
- No severe gastroparesis
- Not pregnant (if of childbearing potential)
Plus any one of:
- Prior myocardial infarction
- Prior ischemic or hemorrhagic stroke
- Symptomatic PAD: intermittent claudication with ABI < 0.85 at rest
- Symptomatic PAD: peripheral arterial revascularization procedure
- Symptomatic PAD: amputation due to atherosclerotic disease
Continuation/Renewal: Wegovy for CV Risk Reduction
All of:
- Continues to be seen by physician specializing in diagnosis or in consultation with a Cardiologist
- Confirmed established cardiovascular disease (same qualifying events as initial)
- HbA1c < 6.5% within past 12 months
- Does NOT have type 1 or type 2 diabetes
- Does NOT have NYHA Class IV heart failure
- Adherence to medication and guideline-directed standard of care for established CV condition
- Requested dose is at least 1.7 mg weekly
- Will be used as adjunct to reduced calorie diet (>= 500 kcal/day) and >= 150 min/week activity
- Failure, contraindication, or intolerance to THREE generic equivalents for at least 3 months each
- No personal or family history of medullary thyroid carcinoma or MEN2
- No prior serious hypersensitivity reaction to semaglutide
- No concomitant use of GLP-1 receptor agonists or GIP/GLP-1 agonists
- No chronic pancreatitis or recent (within 180 days) acute pancreatitis
- No severe gastroparesis
- No sustained increase in resting heart rate
- Not pregnant (if of childbearing potential)
Plus any one of:
- Reduction of >= 5% in body weight from baseline
- Reduction of >= 3% body weight from baseline WITH decrease in LDL or triglycerides
- Reduction of >= 3% body weight from baseline WITH decrease in waist circumference
- Reduction of >= 3% body weight from baseline WITH decrease in blood pressure